A-35 Free Communication/Poster - Epidemiology - Disease Prevention/Treament - Youth: JUNE 1, 2011 7:30 AM - 12:30 PM: ROOM: Hall B
PURPOSE: To investigate the influence of pre-gravid BMI, gestational weight gain, birthweight, physical activity, and body fat on growth trajectory of blood pressure.
METHODS: The participants were 71 children (35 girls, 36 boys) 3.4 to 8.8 years old participating in a 3 year mixed-longitudinal study. A linear growth curve model was used to estimate the influence of pre-gravid BMI, gestational weight gain, birthweight, habitual physical activity, and percent body fatness on mean arterial pressure (MAP).
RESULTS: Significant positive correlation coefficients were found between pre-gravid BMI, gestational weight gain, child's 3-year average percent body fat, and MAP (r = 0.35 to 0.53). In addition, pre-gravid BMI was positively correlated with child birthweight (r = 0.32). The growth curve model showed that both pre-gravid BMI and gestational weight gain were found to significantly predict rate of change of MAP (slope variance = 0.25). Inclusion of the 3-year average physical activity did not improve the predictive utility of the equation, but the 3-year average of percent body fat was positively associated with the rate of change in MAP.
CONCLUSIONS: Children born to mothers with higher pre-gravid BMI and/or gestational weight gain had a greater increase in MAP per unit of age. As the obesity epidemic continues, more mothers are likely to be overweight or obese throughout pregnancy. Thus, the prevention of maternal obesity and excessive weight gain during pregnancy through physical activity and diet intervention may reduce childhood obesity and hypertension.