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Medicine & Science in Sports & Exercise:
doi: 10.1249/01.MSS.0000401526.60348.aa
D-22 Free Communication/Poster - Clinical Exercise Physiology 1 (Clinical Exercise Physiology Association): JUNE 2, 2011 1:00 PM - 6:00 PM: ROOM: Hall B

Novel Measures to Evaluate the Cardiorespiratory Response to Exercise Training Without a Follow-up Exercise Test: 2126: Board #3 June 2 2:00 PM - 3:30 PM

Brawner, Clinton A. FACSM1; Ehrman, Jonathan K. FACSM1; Kerrigan, Dennis J.1; Leon, Arthur S. FACSM2; Rankinen, Tuomo FACSM3; Rao, D.C.4; Bouchard, Claude FACSM3; Keteyian, Steven J. FACSM1

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Author Information

1Henry Ford Hospital, Detroit, MI. 2University of Minnesota, Minneapolis, MN. 3Pennington Biomedical Research Center, Baton Rouge, LA. 4Washington University, St. Louis, MO.

(No relationships reported)

Quantifying the cardiorespiratory response to exercise training (CR-ExT) without a follow-up maximal exercise test is a challenge faced by cardiac rehabilitation programs; a valid measure derived from typical exercise session data would be useful.

PURPOSE: Describe the relationship between changes in novel measures of CR-ExT derived from submaximal exercise data to changes in (a) submaximal measured O2 pulse and (b) peak VO2.

METHODS: This secondary analysis of the HERITAGE Family Study used baseline and follow-up (20 wk exercise training) maximal and submaximal (60% VO2 peak) leg ergometry data, both with respiratory gas analysis (healthy; aged ≥30 yr; n= 306; 43% male). Using work rate from the submaximal test, estimated submaximal VO2 (mL/min) and METs were calculated. Estimated VO2, estimated METs, and submaximal work rate were divided by heart rate and termed estO2pulse, estMET-pulse, and Watt-pulse, respectively.

RESULTS: Baseline peak VO2 was 27.0±6.7 mL/kg/min (mean±SD) and increased 19±10% at follow-up (p<0.001). Submaximal O2 pulse, estO2pulse, MET-pulse, and Watt-pulse increased 19±11%, 24±14%, 25±15%, and 44±35%, respectively (p<0.001 for each). At follow-up, % change of each proposed CR-ExT parameter showed a moderate correlation (0.68-0.78) with % change in submaximal measured O2 pulse, but a lower correlation (0.33-0.45) with % change in peak VO2 (Table).

CONCLUSIONS: Changes in proposed CR-ExT parameters were related to a traditional measure of CR-ExT (i.e., change in submaximal O2 pulse) with SEE of 7-8%. These parameters can be determined using typical exercise session data and could serve as program outcomes; however, this variability may limit ability to accurately evaluate individual patient response.

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