Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
You currently have no recent searches
Farr, Joshua N.1; Van Loan, Marta D.2; Lohman, Timothy G.1; Going, Scott B.1
1University of Arizona, Tucson, AZ. 2University of California, Davis, Davis, CA.
(No relationships reported)
Fat infiltration within skeletal muscle is strongly associated with obesity, type 2 diabetes mellitus, and metabolic syndrome. Lower physical activity may be a risk factor for greater fat infiltration within skeletal muscle, although whether lower physical activity is associated with fat infiltration in otherwise healthy youth is unclear.
PURPOSE: We examined the relationship between physical activity and fat infiltration within skeletal muscle of the calf and thigh in girls.
METHODS: This study was a cross-sectional analysis of the relationship between physical activity and fat infiltration within skeletal muscle in 464 healthy girls aged 8-13 years. Calf and thigh muscle density (mg/cm3), a measure of fat infiltration, was assessed at the 66% tibia and 20% femur sites relative to the respective distal growth plates of the non-dominant limb using peripheral quantitative computed tomography. Physical activity level was classified by past year physical activity questionnaire (PYPAQ) score. Correlations and multiple linear regression were used to assess relationships between physical activity and fat infiltration within skeletal muscle.
RESULTS: Muscle densities of the calf and thigh were inversely correlated with percent total body fat (r = -0.37 to -0.48, all P values < 0.001) and total body fat mass (r = -0.33 to -0.40, all P values < 0.001). Multiple linear regression with physical activity, ethnicity, maturity offset, and muscle size as independent variables showed that physical activity was independently associated with muscle densities of the calf (P < 0.01) and thigh (P < 0.001). Thus, lower physical activity was associated with higher fat infiltration within skeletal muscle.
CONCLUSION: A lower level of physical activity is associated with fat infiltration within skeletal muscle in healthy young girls. Longitudinal studies are needed to confirm these findings.
© 2011 American College of Sports Medicine
Colleague's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at Medicine & Science in Sports & Exercise.
Send a copy to your email
Your message has been successfully sent to your colleague.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection