A-35 Free Communication/Poster - Epidemiology - Disease Prevention/Treament - Youth: JUNE 1, 2011 7:30 AM - 12:30 PM: ROOM: Hall B
The relationship between lifestyle risk factors and cardiometabolic risk factors in adolescents remains less explored.
PURPOSE: We examined the combined effects of healthy lifestyle factors on metabolic syndrome (MS) in 4,022 US adolescents, aged 13 to 19 years, from the National Health and Nutrition Examination Survey (2003-2006).
METHODS: Body weight and height were assessed with standardized protocols. Physical activity was estimated using a physical activity monitor. Plasma vitamin C was measured using isocratic high performance liquid chromatography with electrochemical detection at 650 mV1. We defined a low-risk (healthy lifestyle) profile as physically active (≥60 minutes of moderate or vigorous activity/day), healthy diets (≥50 mmol/L of plasma vitamin C), and normal body weight (BMI <85th percentile for age and sex). We combined these low-risk factors and categorized them as 0, 1, 2, or 3 combined low-risk factors. The metabolic syndrome was defined as 3 or more of the following abnormalities using the modified version of Adult Treatment Panel III definition: abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, high fasting glucose, and hypertension. Multivariable logistic regression was used to investigate the association between combined number of low-risk factors and MS in US adolescents.
RESULTS: After adjustment for age, sex, race, family income, and other multiple risk factors, there was an inverse association between a greater number of low-risk factors and MS (P for trend <0.001). Adolescents who were physically active, had healthy diets, and with a normal BMI had a 97% lower odds of having MS (95% CI, 89%-99%) as compared with adolescents with zero low-risk factors. Adolescents with at least 2 low-risk factors had a 70% (95% CI, 52%-81%) lower odds of having MS when compared with adolescents with 0 low-risk factors.
CONCLUSIONS: Being physically active, eating healthy diets, and maintaining a normal weight is associated with lower risk of MS in US adolescents.