Association Between Lifestyle Factors and Metabolic Syndrome in US Adolescents: 1347: Board #83 June 1 9:30 AM - 11:00 AM

Greer, Jennifer; Lee, Chong-Do FACSM; Kang, Hoyul

Medicine & Science in Sports & Exercise: May 2011 - Volume 43 - Issue 5 - p 272
doi: 10.1249/01.MSS.0000400747.81967.b8
A-35 Free Communication/Poster - Epidemiology - Disease Prevention/Treament - Youth: JUNE 1, 2011 7:30 AM - 12:30 PM: ROOM: Hall B

1Arizona State University, Mesa, AZ. 2Kyungpook National University, Daegu, Korea, Republic of.

(No relationships reported)

The relationship between lifestyle risk factors and cardiometabolic risk factors in adolescents remains less explored.

PURPOSE: We examined the combined effects of healthy lifestyle factors on metabolic syndrome (MS) in 4,022 US adolescents, aged 13 to 19 years, from the National Health and Nutrition Examination Survey (2003-2006).

METHODS: Body weight and height were assessed with standardized protocols. Physical activity was estimated using a physical activity monitor. Plasma vitamin C was measured using isocratic high performance liquid chromatography with electrochemical detection at 650 mV1. We defined a low-risk (healthy lifestyle) profile as physically active (≥60 minutes of moderate or vigorous activity/day), healthy diets (≥50 mmol/L of plasma vitamin C), and normal body weight (BMI <85th percentile for age and sex). We combined these low-risk factors and categorized them as 0, 1, 2, or 3 combined low-risk factors. The metabolic syndrome was defined as 3 or more of the following abnormalities using the modified version of Adult Treatment Panel III definition: abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, high fasting glucose, and hypertension. Multivariable logistic regression was used to investigate the association between combined number of low-risk factors and MS in US adolescents.

RESULTS: After adjustment for age, sex, race, family income, and other multiple risk factors, there was an inverse association between a greater number of low-risk factors and MS (P for trend <0.001). Adolescents who were physically active, had healthy diets, and with a normal BMI had a 97% lower odds of having MS (95% CI, 89%-99%) as compared with adolescents with zero low-risk factors. Adolescents with at least 2 low-risk factors had a 70% (95% CI, 52%-81%) lower odds of having MS when compared with adolescents with 0 low-risk factors.

CONCLUSIONS: Being physically active, eating healthy diets, and maintaining a normal weight is associated with lower risk of MS in US adolescents.

© 2011 American College of Sports Medicine