F-28 Free Communication/Poster - Physical Activity and Chronic Disease: MAY 29, 2009 1:00 PM - 6:00 PM ROOM: Hall 4F
South Asians (SA) living in England (originating from India, Bangladesh and Pakistan) have a higher incidence of diabetes and coronary heart disease compared with the white population. The role of physical activity in reducing cardiovascular disease (CVD) risk among SA remains poorly understood.
PURPOSE: To examine the association between physical activity and CVD risk markers in a representative sample of SA and whites living in England.
METHODS: Participants were 13,851 healthy (no history of CVD) men and women (3,550 SA, 10,301 white; 45 ± 17 yrs old) drawn from the Health Survey for England. CVD risk factors included fasting glucose (fGL) and triglycerides (fTG), glycosylated haemoglobin (HbA1c), C-reactive protein (CRP), fibrinogen, cholesterol (C), waist circumference (WC), and mean arterial blood pressure (MAP). Self-reported questionnaires were employed to estimate physical activity levels. Participants were deemed to be sufficiently active if they reported at least 450 MET-min per week.
RESULTS: In comparison with whites, the SA were less likely to meet the physical activity guidelines (odds ratio = 0.41, 95% CI, 0.38 to 0.45). In general linear models that were adjusted for age and gender, SA had higher levels of fGL, fTG, HbA1c, CRP, and lower HDL-C compared with whites. In comparison with inactive SA, the active SA demonstrated lower fTG (adjusted beta, -0.19, 95% CI, -0.35 to -0.04, P=0.02), HbA1c (-0.09, -0.18 to -0.01, P=0.03), CRP (-0.48, -0.10 to 0.01, P=0.05), WC (-1.59, -2.38 to -0.81, P=0.001), MAP (-1.97, -3.29 to -0.66, P=0.003), and greater HDL-C (0.08, 0.05 to 0.11, P=0.001). Similar associations were observed in physically active whites compared to the sedentary.
CONCLUSIONS: Physical activity is associated with some important CVD risk markers in an at risk SA population. Physical activity should be promoted in SA living in England.