Abstracts: American College of Sports Medicine Conference on Integrative Physiology of Exercise: THURSDAY, SEPTEMBER 28, 2006: POSTER SESSION 1: Cardiovascular
Sports training may lower the risk for coronary artery disease (CAD) by mitigating inflammation, which plays a key role in the pathophysiology of atherosclerosis. The purpose of this study was to determine the effect of sports training composed with whole body enduring and partial muscular power training on level of inflammatory adipocytokine as interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), leptin, and high sensitive C-reactive protein (hs CRP) in obese SSireum athletes which is traditional Korea sports alike Sumo in Japan.
Subjects were 20-27 year-old male students, who were classified into four groups by BMI (below 24.9kg/m2 or over 25.0kg/m2) and sports training (athletes or non-athletes); Normal BMI-Non Athletes (Control, n=9), Obese-Non Athletes (Obesity, n=9), Normal BMI-Athletes (Athletes, n=8), Obese Athletes (n=10). Athletes were training for every 3-6 hours during 5-7days with near exhausted level in sand place field, but non-athletes were sedentary students without the physical training and any experience. Data were analysed by ANOAV (α=.05).
BMI were 22.8±1.6kg/m2 in Control, 27.2±2.2kg/m2 in Obesity, 22.1±1.5kg/m2 in Athletes and 29.9±2.1kg/m2 in Obese Athletes. IL-6 were 2.77±1.60pg/ml in Control, 3.38±2.04pg/ml in Obesity, 0.39±0.69pg/ml in Athletes and 1.53±1.86pg/ml in Obese Athletes, in which IL-6 of Athletes and Obese Athletes were significantly differed from Non-Athletes groups (p<.05). TNF-α were 6.66±2.90pg/ml in Control, 11.04±5,45pg/ml in Obesity, 6.43±4.44pg/ml in Athletes and 6.63±2.19pg/ml in Obese Athletes, in which TNF-α of other 3 groups were significantly differed from Obesity (p<.05). Leptin were 1.94±0.76mg/dl in Control, 3.51±1.75mg/dl in Obesity, 0.75±0.27mg/dl in Athletes and 3.15±1.02mg/dl in Obese Athletes, in which Leptin of Control and Athletes were significantly differed from Obesity and Obese Athletes(p<.05). hs CRP were 6.3±2.5×10−3mg/dl in Control, 7.5±5.0×10−3mg/dl in Obesity, 5.0±1.4×10−3mg/dl in Athletes and 9.6±6.1×10−3mg/dl in Obese Athletes, in which hs CRP of Athletes was significantly differed from Obesity(p<.05).
Obese young students had elevated serum levels of IL-6, TNF-α, Leptin and hs CRP in this study, that these variables known markers of inflammation and cardiovascular risk factor were closely associated with obese state. But it was confirmed that those risk were reduced with physical training as like Obese Athletes. However, these results indicate that the favorable effects from physical training in obese Ssireum athletes are disappeared because of their obesity.