F-22D Free Communication/Slide Cardiac Rehabilitation
Moderate intensity exercise increases functional capacity in patients with congestive heart failure (CHF). However, few data are available regarding the effect of such programs on traditional cardiovascular disease (CVD) risk factors in this patient subset.
In this multicenter study, we investigated the effect of a contemporary phase 2 cardiac rehabilitation program on multiple CVD risk factors in patients with (Group A, n=161) and without (Group B, n=1367) a history of CHF.
Outcome measures were evaluated at baseline and after approximately 12 weeks of participation in a phase 2 cardiac rehabilitation program at 12 centers in the U.S.
On program exit, improvements (p < 0.05, unless otherwise indicated) in multiple CVD risk factors were noted for patients in both groups who had abnormal baseline risk factor values (based on national guidelines), as follows: systolic/diastolic blood pressure (Group A, −19/13 mmHg; Group B, −20/18 mmHg); LDL cholesterol (Group A, −36 mg/dl; Group B, −46 mg/dl); HDL cholesterol (Group A, 1 mg/dl, p = NS; Group B, 5 mg/dl); triglycerides (Group A, −15 mg/dl, p = NS; Group B, −47 mg/dl); fasting glucose (Group A, −44 mg/dl; Group B, −19 mg/dl); and weight (Group A, −3 lbs; Group B, −3 lbs). The increase in HDL cholesterol and decrease in diastolic blood pressure were significantly greater (p < 0.05) in Group B as compared with Group A participants.
Although additional research is warranted, these observations suggest that while patients with and without a history of CHF substantially improve multiple CVD risk factors during participation in a phase 2 cardiac rehabilitation program, the magnitude of improvement may be less for certain risk factors in patients with a history of CHF.