Skip Navigation LinksHome > May 1999 - Volume 31 - Issue 5 > DETERMINANTS OF EXERCISE TOLERANCE AFTER ACUTE MYOCARDIAL IN...
Medicine & Science in Sports & Exercise:
Annual Meeting Abstracts

DETERMINANTS OF EXERCISE TOLERANCE AFTER ACUTE MYOCARDIAL INFARCTION IN OLDER PERSONS.

Marchionni, N.; Fattirolli, F.; Fumagalli, S.; Cartei, A.; Burgisser, C.; Del Lungo, F.; Diogini, F.; Castagna, R.; Masotti, G.; Oldridge, N.

Free Access
Article Outline
Collapse Box

Author Information

Gerontology and Geriatric Medicine, University of Florence, Florence, Italy.

[Sponsor; N. Oldridge, FACSM].

Abstract 514

Although all randomized controlled trials [RCT] of cardiac rehabilitation [CR] after myocardial infarction [MI] have systematically excluded older persons, the age-related reduction in exercise tolerance [TWC, Kg.m] has been confirmed in observational and controlled, but not randomized, studies. We designed a RCT to compare the efficacy of 8-weeks of CR in middle-aged [45-65 years; n=89; mean age=57 years], elderly [66-75 years; n=90; mean age 70 years], and old-old [76-85 years; n=86; mean age=80 years]. In this analysis, we report on the factors which are independent determinants of baseline TWC. Baseline TWC was lower [p<0.001] in the old-old patients [1634 Kg.m] than either the elderly [2748 Kg.m] or the middle-age patients [4642 Kg.m]. With univariate analysis, a series of variables were identified as potential confounders between baseline TWC and age. Using backward stepwise regression analysis, age, gender, body surface area, intensity of physical activity pre-MI, and depressive symptom scores were independently related to TWC [R2=0.43; p<0.001] with age explaining 70% of the observed variance. We calculated the average decrement in TWC per decade between 45 and 85 years of age as 1285 Kg.m/decade in the unadjusted model and as 922 Kg.m/decade in the final adjusted model. These data confirm the previously reported strong association between age and TWC. Other variables included in the model provide information that is both relevant and important in optimizing care in the early stages of recovery and for making decisions about referral to CR for older post-MI patients.

Supported by a grant from the Italian National Research Council [SP5]

Back to Top | Article Outline

Section Description

American College of Sports Medicine; 46th Annual Meeting; Washington State; Convention & Trade Center; June 2-5, 1999

The abstracts contained herein were prepared by the authors and then printed by photo-offset without correction. The accuracy, form of citation, designation, nomenclature, and the like, all remain the responsibility of the author. Readers should note that the appearance of an abstract does not imply future publication of a regular scientific manuscript.

B-48 SLIDE EXER EVAUA IN PERSONS WITH & WITHOUT CARDIOVASCULAR DISEASE

© 1999 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Article Level Metrics

Connect With Us