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00005768-200805001-0069000005768_2008_40_s1_kuk_measurement_5miscellaneous< 19_0_1_2 >Medicine & Science in Sports & Exercise©2008The American College of Sports MedicineVolume 40(5) Supplement 1May 2008p S1Influence of Measurement Site on the Association between Visceral Adipose Tissue with Metabolic Risk: 514: May 28 9:45 AM - 10:00 AM[A-13 Free Communications/Slide - Body Composition: May 28 9:30 AM - 11:15 AM; ROOM: 103]Kuk, Jennifer L.1; Church, Timothy S.2; Blair, Steven N. FACSM3; Ross, Robert41York University, Toronto, ON, Canada. 2Pennington Biomedical Research Center Louisiana State University System, Baton Rouge, LA. 3University of South Carolina, Columbia, SC. 4Queen's University, Kingston, ON, Canada.Email: jennkuk@yorku.ca(No relationships reported)PURPOSE: To determine the utility of a single cross-sectional image (area) measured at specific anatomical landmarks to predict total visceral and abdominal subcutaneous adipose tissue (VAT and ASAT) volume as determined by a multiple image protocol, and metabolic risk. Second, to examine the ability of these measures to predict changes in total abdominal AT volume and changes in metabolic risk.METHODS: Total VAT and ASAT volume was derived using approximately 35 contiguous computed tomography (CT) images from T10-T11 to L5-S1 in 67 overweight or obese postmenopausal women at baseline and after a 6 month exercise intervention (n=40). CT images obtained at 8 intervertebral locations (e.g., L4-L5, L3-L4, etc) were used to determine associations between a single area and total AT volume.RESULTS: There was a tendency for VAT measured at L2-L3 and L3-L4 to be most strongly associated with total VAT volume, changes in VAT volume (Figure 1) and metabolic risk at baseline (Figure 2). Measurement landmark generally did not influence the association between total ASAT volume or metabolic risk. With few exceptions, the magnitude of change in VAT and ASAT (area or volume) were not associated with changes in metabolic risk regardless of measurement site (P>0.10).Figure. No caption available.Figure. No caption available.CONCLUSIONS: Measurement site for VAT, but not ASAT has subtle influences the magnitude of the association with the respective total AT volume and changes therein. Accordingly, there was a tendency for VAT measured at L2-L3 and L3-L4 to be most strongly associated with health risk.This work was supported by a grant from the National Institutes of Health to Steven Blair (AG06945).Influence of Measurement Site on the Association between Visceral Adipose Tissue with Metabolic Risk: 514: May 28 9:45 AM - 10:00 AMKuk, Jennifer L.; Church, Timothy S.; Blair, Steven N. FACSM; Ross, RobertA-13 Free Communications/Slide - Body Composition: May 28 9:30 AM - 11:15 AM; ROOM: 103540