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00005768-200605001-0314500005768_2006_38_s545_wolf_oxidation_5abstract< 15_0_1_0 >Medicine & Science in Sports & Exercise© 2006 American College of Sports MedicineVolume 38(5) SupplementMay 2006p S545–S546Effects of Exercise Training on Fat Oxidation in Obese Women: 2811: Board#85 9:00 AM – 10:00 AM[Saturday Morning Poster Presentations: Posters displayed from 7:30–11:00 a.m.: One-hour author presentation times are staggered from 8:00–9:00 a.m., 9:00–10:00 a.m., and 10:00–11:00 a.m.: G-15 Free Communication/Poster – Fat Metabolism: SATURDAY, JUNE 3, 2006 8:00 AM – 11:00 AM ROOM: Hall B]Wolf, Donna L.; Fleet, Sara; Grove, George; Jakicic, John M. FACSM; Goodpaster, Bret H.University of Pittsburgh, Pittsburgh, PA.Email: wolfd@dom.pitt.edu Reduced energy expenditure and impaired fat oxidation are critical factors associated with obesity. Although much is known about the effects of exercise training on fat metabolism in normal weight, healthy women, considerably less is known about the potential benefits of exercise on fat metabolism in obesity.PURPOSE: To determine the effects of aerobic exercise on fat metabolism and body composition in previously sedentary obese women.METHODS: 13 Obese (BMI > 30 kg/m2) premenopausal women, aged 38 ± 7 years completed a 16- week intervention consisting of moderate exercise (3–4 sessions/week, 30–50 minutes/session, at 60–70 VO2 max). Pre and post intervention, all subjects underwent a DXA scan to determine body composition, graded exercise test to determine maximal oxygen uptake (VO max), and indirect calorimetry to measure energy expenditure and fat oxidation at rest and during exercise (treadmill walking at 55% VO2 max).RESULTS: VO2max improved on average by 10.1% from 50.9 ± 8.2 to 56.1 ± 8.1 ml/kgFFM/min; (p<0.01). There was a slight decrease in fat mass from 38.0 ± 6.9 kg to 36.2 ± 6.7 kg (p<0.05). There was an increased rate of fat oxidation during 60 minutes of sub-maximal exercise (0.30 to 0.34 g/min; p<0.05). There was, however, no change in resting metabolic rate (RMR) or resting fat oxidation.CONCLUSION: In obese premenopausal women, 16 weeks of moderate exercise enhanced fatty acid oxidation during sub-maximal exercise, but did not alter RMR or resting rates of fat oxidation. Supported by a grant from Experimental and Applied Sciences, Inc.Effects of Exercise Training on Fat Oxidation in Obese Women: 2811: Board#85 9:00 AM – 10:00 AMWolf, Donna L.; Fleet, Sara; Grove, George; Jakicic, John M. FACSM; Goodpaster, Bret H.Saturday Morning Poster Presentations: Posters displayed from 7:30-11:00 a.m.: One-hour author presentation times are staggered from 8:00-9:00 a.m., 9:00-10:00 a.m., and 10:00-11:00 a.m.: G-15 Free Communication/Poster - Fat Metabolism: SATURDAY, JUNE 3, 2006 8:00 AM - 11:00 AM ROOM: Hall B538