Skip Navigation LinksHome > Published Ahead-of-Print > Alternating Bouts of Sitting and Standing Attenuates Postpra...
Medicine & Science in Sports & Exercise:
doi: 10.1249/MSS.0000000000000337
Original Investigation: PDF Only

Alternating Bouts of Sitting and Standing Attenuates Postprandial Glucose Responses.

Thorp, Alicia A.; Kingwell, Bronwyn A.; Sethi, Parneet; Hammond, Louise; Owen, Neville; Dunstan, David W.

Published Ahead-of-Print
Collapse Box


Purpose: To examine whether reductions in sitting time through alternating 30 minute bouts of sitting and standing can reduce postprandial glucose, insulin and triglyceride responses.

Methods: Twenty-three overweight/obese sedentary office workers (17 males; 6 females; mean +/- SD; age: 48.2 +/- 7.9 yrs, BMI: 29.6 +/- 4.0 kg/m2) undertook two, short-term (5-day) experimental conditions in an equal, randomised (1:1) order. In a simulated office environment, participants performed typical occupational tasks for 8 hours/day while in a: 1) seated work posture (control condition); or, 2) interchanging between a seated and standing work posture every 30 minutes using an electric, height-adjustable workstation (intervention condition). Fasting and postprandial blood samples after a mixed test drink were collected hourly for 4 hours on Day 1 and 5 of each condition to assess serum insulin, plasma glucose and triglycerides. Dietary intake (KJ/d) and physical activity were standardised during each condition. The trial was registered with the Australian New Zealand Clinical Trials Registry (ACTRN12611000632998).

Results: Following adjustment for time (Day 1 and Day5), incremental area under the analyte time curve (iAUC) differed significantly between conditions for plasma glucose (P=0.007) but not for serum insulin or plasma triglycerides. Adjusted mean glucose iAUC was lowered by 11.1% after the intervention condition (6.38mmol/L[middle dot]h [CI: 5.04, 7.71] ) relative to the control condition (7.18mmol/L[middle dot]h [CI: 5.85, 8.52] ). No temporal changes (Day 1 vs Day 5) between conditions were observed.

Conclusion: Alternating standing and sitting in 30 minute bouts results in modest beneficial effects on postprandial glucose responses in overweight/obese office workers.

(C) 2014 American College of Sports Medicine


Article Tools


Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us