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Measured versus Self-reported Physical Function in Adult Survivors of Childhood Cancer

SMITH, WEBB A.1,2; LI, ZHENGHONG1; LOFTIN, MARK2; CARLYLE, BRENT E.3; HUDSON, MELISSA M.1,4; ROBISON, LESLIE L.1; NESS, KIRSTEN K.1

Medicine & Science in Sports & Exercise: February 2014 - Volume 46 - Issue 2 - p 211–218
doi: 10.1249/MSS.0b013e3182a65c73
Clinical Sciences

Purpose: Childhood cancer survivors (CCS) experience late effects that interfere with physical function. Limitations in physical function can affect CCS abilities to actively participate in daily activities. The purpose of this investigation was to evaluate the concordance between self-reported physical performance and clinically evaluated physical performance among adult CCS.

Methods: CCS 18 yr or older and 10 yr or older from diagnosis who are participants in the St. Jude Lifetime cohort study responded to the physical function section of the Medical Outcome Survey Short Form (SF-36). Measured physical performance was evaluated using the Physical Performance Test and the 6-Minute Walk Test.

Results: Individuals (N = 1778, 50.8% female) with a median time since diagnosis of 24.9 yr (range = 10.9–48.2) and a median age of 32.4 yr (range = 19.1–48.2) completed testing. Limitations in physical performance were self-reported by 14.1% of participants. The accuracy of self-report physical performance was 0.87 when the SF-36 was compared with the 6-Minute Walk Test or the Physical Performance Test. Reporting inaccuracies most often involved reporting a physical performance limitation. Poor accuracy was associated with previous diagnosis of a bone or CNS tumor, lymphoma, older age, and large body size.

Conclusions: These results suggest that self-report, using the physical performance subscale of the SF-36, correctly identifies CCS who do not have physical performance limitations. In contrast, this same measure is less able to identify individuals who have performance limitations.

1Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, Memphis, TN; 2Departments of Health, Exercise Science, and Recreation, University of Mississippi, University, MS; 3Department of Urology, The Ohio State University College of Medicine, Columbus, OH; and 4Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN

Address for correspondence: Webb A. Smith, MS, Department of Epidemiology and Cancer Control, St. Jude Children’s Hospital, 262 Danny Thomas Place, MS735, Memphis, TN 38105-2794; E-mail: Webb.smith@stjude.org.

Submitted for publication March 2013.

Accepted for publication July 2013.

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© 2014 American College of Sports Medicine