Regular Maternal Exercise Dose and Fetal Heart Outcome

MAY, LINDA E.1; SUMINSKI, RICHARD R.2; LANGAKER, MICHELLE D.3; YEH, HUNG-WEN4; GUSTAFSON, KATHLEEN M.5

Medicine & Science in Sports & Exercise: July 2012 - Volume 44 - Issue 7 - p 1252–1258
doi: 10.1249/MSS.0b013e318247b324
Basic Sciences

Purpose: Our previous research found lower fetal HR and increased HR variability (HRV) in women who exercised during pregnancy. This finding is similar to the adult heart training response at rest due to aerobic exercise. Dose–response associations have been found between physical activity and cardiorespiratory fitness in adults. Therefore, our objective was to determine whether there is a dose–response relationship between maternal physical activity and fetal HR, HRV, and sympathovagal balance.

Methods: Pregnant women completed a physical activity questionnaire and magnetocardiogram (magnetic correlate to ECG) recordings at 36-wk gestational age. Women reported the duration, intensity, and frequency of each activity for each month of pregnancy as well as 3 months before pregnancy. These values were used to calculate maternal physical activity measures for each participant. Relationships between fetal HR, HRV, and sympathovagal balance at 36-wk gestational age and maternal physical activity (n = 50 pairs) during the third trimester were assessed by Spearman correlations. Regression analysis was performed to further examine these relationships after controlling for maternal and fetal covariates (maternal age, maternal resting HR, maternal weight gain, prepregnancy body mass index (BMI), and fetal activity state).

Results: The regression analyses showed that maternal physical activity intensity (kcal·min−1) was negatively associated with HR in the active fetal state (P < 0.05), and physical activity duration (minutes during the third trimester) was positively associated with fetal HRV (P < 0.05). There were no statistically significant relationships with maternal physical activity on measures of fetal sympathovagal balance.

Conclusions: Maternal physical activity dose during the third trimester is associated with resting fetal heart effects similar to a trained response. Future studies on the health benefits of this fetal response are highly warranted.

1Department of Anatomy & Physiology, Kansas City University of Medicine and Biosciences, Kansas City, MO; 2Department of Physiology, Kansas City University of Medicine and Biosciences, Kansas City, MO; 3Deparment of Obstetrics and Gynecology, Kansas City University of Medicine and Biosciences, Kansas City, MO; 4Department of Biostatistics, School of Medicine, University of Kansas Medical Center, Kansas City, KS; and 5Hoglund Brain Imaging Center, Department of Neurology, School of Medicine, University of Kansas Medical Center, Kansas City, KS

Address for correspondence: Linda E. May, M.S., Ph.D., Department of Anatomy & Physiology, Kansas City University of Medicine and Biosciences, 1750 Independence Ave., Office of Community Health Research (OCHR), SEP 464, Kansas City, MO 64106; E-mail: lmay@kcumb.edu.

Submitted for publication September 2011.

Accepted for publication December 2011.

©2012The American College of Sports Medicine