Effect of Exercise Training on Physical Fitness in Type II Diabetes Mellitus

LAROSE, JOANIE1; SIGAL, RONALD J.2,4; BOULÉ, NORMAND G.5; WELLS, GEORGE A.2; PRUD'HOMME, DENIS1; FORTIER, MICHELLE S.1; REID, ROBERT D.2,3; TULLOCH, HEATHER2,3; COYLE, DOUGLAS2; PHILLIPS, PENNY2; JENNINGS, ALISON2; KHANDWALA, FARAH3; KENNY, GLEN P.1,2

Medicine & Science in Sports & Exercise: August 2010 - Volume 42 - Issue 8 - pp 1439-1447
doi: 10.1249/MSS.0b013e3181d322dd
Clinical Sciences

Few studies have compared changes in cardiorespiratory fitness between aerobic training only or in combination with resistance training. In addition, no study to date has compared strength gains between resistance training and combined exercise training in type II diabetes mellitus (T2DM).

Purpose: We evaluated the effects of aerobic exercise training (A group), resistance exercise training (R group), combined aerobic and resistance training (A + R group), and sedentary lifestyle (C group) on cardiorespiratory fitness and muscular strength in individuals with T2DM.

Methods: Two hundred and fifty-one participants in the Diabetes Aerobic and Resistance Exercise trial were randomly allocated to A, R, A + R, or C. Peak oxygen consumption (V˙O2peak), workload, and treadmill time were determined after maximal exercise testing at 0 and 6 months. Muscular strength was measured as the eight-repetition maximum on the leg press, bench press, and seated row. Responses were compared between younger (aged 39-54 yr) and older (aged 55-70 yr) adults and between sexes.

Results: V˙O2peak improved by 1.73 and 1.93 mL O2·kg−1·min−1 with A and A + R, respectively, compared with C (P < 0.05). Strength improvements were significant after A + R and R on the leg press (A + R: 48%, R: 65%), bench press (A + R: 38%, R: 57%), and seated row (A + R: 33%, R: 41%; P < 0.05). There was no main effect of age or sex on training performance outcomes. There was, however, a tendency for older participants to increase V˙O2peak more with A + R (+1.5 mL O2·kg−1·min−1) than with A only (+0.7 mL O2·kg−1·min−1).

Conclusions: Combined training did not provide additional benefits nor did it mitigate improvements in fitness in younger subjects compared with aerobic and resistance training alone. In older subjects, there was a trend to greater aerobic fitness gains with A + R versus A alone.

1School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, CANADA; 2Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, CANADA; 3University of Ottawa Heart Institute, Prevention and Rehabilitation Centre, Ottawa, Ontario, CANADA; 4Departments of Medicine, Cardiac Sciences and Community Health Sciences, Faculties of Medicine and Kinesiology, The University of Calgary, Calgary, Alberta, CANADA; and 5Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Alberta, CANADA

Address for correspondence: Glen P. Kenny, Ph.D., University of Ottawa, School of Human Kinetics, 125 University, Montpetit Hall, Ottawa, Ontario, Canada K1N 6N5; E-mail: gkenny@uottawa.ca.

Submitted for publication November 2009.

Accepted for publication January 2010.

©2010The American College of Sports Medicine