Purpose: To determine the effect of exercise based on a multiple purpose, high-intensity philosophy on parameters of metabolic syndrome (MetS) in older females with the MetS.
Methods: Thirty-two women (68.7 ± 3.4 yr) with the MetS according to the International Diabetes Federation (IDF) took part in the exercise training (EG), and 33 females (69.5 ± 4.3 yr) also with MetS served as control group (CG). Beside the diagnostic tools of the MetS (waist circumference, triglycerides, HDL-C, blood pressure, and glucose), corresponding anthropometric parameters, total cholesterol, and high-sensitivity C-reactive protein (hsCRP) were determined.
Results: After 12 months of exercise, significant effects were observed for total body fat [EG: −1287 g vs CG: +484 g; P = 0.001; confidence interval (CI) = −2787 to −744 g], trunk fat (−1070 vs −203 g; P = 0.005; CI = −1460 to −274 g), hip circumference (−2.1 vs +1.0 cm; P = 0.001; CI = −4.8 to −1.3 cm), triglycerides: (−24.1 vs −0.3 mg·dL−1; P = 0.021; CI = −43.9 to −3.7 mg·dL−1), total cholesterol: (−19.8 vs +0.2 mg·dL−1; P = 0.008; CI = −34.6 to −5.5 mg·dL−1), and HDL-C: (+3.8 vs −0.2 mg·dL−1; P = 0.036; CI = 0.3 to 7.6 mg·dL−1). Waist circumference slightly decreased in both groups (EG: −0.7% vs CG: −0.6%; P = 0.94). Resting systolic (−7.1 vs −6.4 mm Hg; P = 0.84) and diastolic (−8.0 vs −+9.8 mm Hg; P = 0.39) blood pressure significantly decreased in both groups. Changes of glucose and hsCRP did not significantly vary between groups (glucose: +0.7 vs +1.0 mg·dL−1, P = 0.88; hsCRP: −0.68 vs −0.50 mg·L−1, P = 0.36). The number of criteria of the MetS significantly decreased in the EG (4.13-3.66) and slightly decreased in the CG (4.12-3.97); however, significant time group interactions were not observed (P = 0.15; CI = −0.74 to 0.12).
Conclusion: Our multipurpose exercise program significantly affects most parameters of the MetS in elderly women.
Institute of Medical Physics, University of Erlangen, GERMANY
Address for correspondence: Wolfgang Kemmler, Ph.D., Institute of Medical Physics, University of Erlangen, Henkestrasse 91, 91052 Erlangen, Germany; E-mail: firstname.lastname@example.org.
Submitted for publication June 2008.
Accepted for publication July 2008.