We examined the influence of self-administered anabolic androgenic steroids(AAS) on the lipogram of male body builders. Serum lipoprotein (a) (Lp(a)), total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels were measured in 10 experimental and 8 control male competitive body builders. The proportion of subiects with serum Lp(a) levels above 30 mg·dl-1 was significantly lower in the AAS group than the non-AAS group. HDL-C levels were significantly lower and LDL-C levels significantly higher in the AAS group than the non-AAS group. These data suggest that AAS in male body builders have a beneficial effect on serum Lp(a) levels but reduce the HDL-C:LDL-C ratio.
Department of Physiology, University of the Witwatersrand Medical School, Parktown, Johannesburg, 2193 SOUTH AFRICA
Submitted for publication July 1994.
Accepted for publication June 1995.
Grant support was provided by The South African Institute of Medical Research and the Iris Ellen Hodges Cardiovascular Research Trust.
Address for correspondence: Larry Cohen, Department of Physiology, University of the Witwatersrand Medical School, 7 York Road, Parktown, Johannesburg, 2193 South Africa.