Hemodynamic patterns and duration of post-dynamic exercise hypotension in hypertensive humans

RUECKERT, PATRICIA A.; SLANE, PETER R.; LILLIS, DIANE L.; HANSON, PETER

Medicine & Science in Sports & Exercise:
Clinical Sciences: Clinical Investigations
Abstract

We investigated: 1) the mechanism of the hypotensive effect of a single bout of dynamic exercise in hypertensive subjects by measuring hemodynamic parameters before and for 2 h after treadmill exercise, and 2) the duration of the effect using ambulatory blood pressure (BP) monitoring once the subjects left the test site. Ten minutes after exercise there was a significant decrease from baseline systolic pressure (SP; -14 ± 3 mm Hg), mean arterial pressure (MAP; -7 ± 2 mm Hg), total peripheral resistance(TPR; -3.7 ± 1.2 units), calf vascular resistance (CVR; -25.4 ± 4.1 units), and an increase in HR (19 ± 2 bpm). The changes in SP, DP, MAP, and HR were maintained during the 2 h of post-exercise monitoring; CVR remained decreased for 1 h; TPR returned to baseline within 20 min and then tended to be slightly elevated. CO was significantly decreased at 50, 60, and 120 min after exercise. We conclude that the early decline in BP after dynamic exercise in hypertensive subjects follows a biphasic pattern: 1) an initial decrease in total and regional vascular resistance with maintained CO, 2) followed by increasing resistance and decrease CO. Pre-exercise hypertensive BP values returned during subsequent ambulatory monitoring.

Author Information

Department of Medicine, Cardiology Section, University of Wisconsin Medical School, Madison, WI 53792-3248

Submitted for publication February 1995.

Accepted for publication August 1995.

We thank the patients who participated in this study and Shari Clark for her technical assistance with the hemodynamic measurements.

Address for correspondence: Patricia A. Rueckert, Ph.D., Cardiology Section H6/349, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792-3248.

©1996The American College of Sports Medicine