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Genetic Roles in Muscle Strength

Kostek, Matthew M.S.; Hubal, Monica J. Ph.D.; Pescatello, Linda S. Ph.D., FACSM

ACSM's Health & Fitness Journal: March-April 2007 - Volume 11 - Issue 2 - p 18-23
doi: 10.1249/01.FIT.0000262475.20949.bc

Learning Objective The primary learning objective for this article is to familiarize the health/fitness professional with basic genetic terminology and to review current knowledge about genetic contributions to human muscular strength.

This article reviews basic concepts in genetics and summarizes recent findings concerning associations between specific genes and human muscle strength.

Matthew Kostek, M.S., is a Ph.D. student at the Kinesiology Department of the University of Connecticut, where his research focuses on the physiological and genetic impact on physical fitness as well as genetic and behavioral contributions to exercise adoption and maintenance. He is ACSM Health/Fitness Instructor® certified.

Monica Hubal, Ph.D., is currently a postdoctoral fellow in the Research Center for Genetic Medicine at the Children's National Medical Center, where her research focuses on the underlying genetic and molecular mechanisms of skeletal muscle adaptation.

Linda Pescatello, Ph.D., FACSM, CPD, is a professor of Health Promotion and director of the Center for Health Promotion at the University of Connecticut. She holds joint appointments in the Departments of Kinesiology, Nutritional Sciences, and Physiology and Neurobiology at the University of Connecticut. Her research focuses on the physiological and genetic explanations of the health benefits of physical activity, particularly relating to hypertension.

© 2007 American College of Sports Medicine