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Arterial Ventricular Uncoupling With Age and Disease and Recoupling With Exercise

Chantler, Paul D.

Exercise & Sport Sciences Reviews:
doi: 10.1249/JES.0000000000000100

The deterioration in arterial and cardiac function with aging impairs arterial ventricular coupling, an important determinant of cardiovascular performance. However, exercise training improves arterial ventricular coupling especially during exercise. This review examines the concept of arterial-ventricular coupling and how age and disease uncouples, but exercise training recouples, the heart and arterial system.

In Brief

Can exercise training recouple the interaction between the heart and arterial system.

Author Information

1Division of Exercise Physiology, School of Medicine; and 2Center for Cardiovascular and Respiratory Sciences, Health Sciences Center, West Virginia University, Morgantown, WV

Address for correspondence: Paul D. Chantler, Ph.D., Robert C. Byrd Health Sciences Center, Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV 26506 (E-mail:

Accepted for publication: October 17, 2016

Editor: Hirofumi Tanaka, Ph.D., FACSM

© 2017 American College of Sports Medicine