Skip Navigation LinksHome > April 2014 - Volume 42 - Issue 2 > Fiber Typing in Aging Muscle
Exercise & Sport Sciences Reviews:
doi: 10.1249/JES.0000000000000012
Articles

Fiber Typing in Aging Muscle

Purves-Smith, Fennigje M.1; Sgarioto, Nicolas2; Hepple, Russell T.1,2,3

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Abstract

It is accepted widely that fast-twitch muscle fibers are preferentially impacted in aging muscle, yet we hypothesize that this is not valid when aging muscle atrophy becomes severe. In this review, we summarize the evidence of fiber type-specific effect in aging muscle and the potential confounding roles of fibers coexpressing multiple myosin heavy-chain isoforms and their histochemical identification.

© 2014 American College of Sports Medicine

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