Skip Navigation LinksHome > January 2014 - Volume 42 - Issue 1 > MRI Reveals Brain Abnormalities in Drug-Naive Parkinson’s Di...
Exercise & Sport Sciences Reviews:
doi: 10.1249/JES.0000000000000003
Articles

MRI Reveals Brain Abnormalities in Drug-Naive Parkinson’s Disease

Planetta, Peggy J.1; McFarland, Nikolaus R.2,3; Okun, Michael S.2,3,4; Vaillancourt, David E.1,2,5

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Abstract

Most brain studies of Parkinson’s disease (PD) focus on patients who are already taking antiparkinsonian medication. This makes it difficult to isolate the effects of disease from those of treatment. We review magnetic resonance imaging evidence supporting the hypothesis that early-stage untreated PD patients have structural and functional abnormalities in the brain, some of which are related to motor symptoms.

© 2014 American College of Sports Medicine

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