Exercise and Sport Sciences Reviews

Skip Navigation LinksHome > October 2012 - Volume 40 - Issue 4 > Effect of Statins on Skeletal Muscle: Exercise, Myopathy, a...
Exercise & Sport Sciences Reviews:
doi: 10.1097/JES.0b013e31826c169e

Effect of Statins on Skeletal Muscle: Exercise, Myopathy, and Muscle Outcomes

Parker, Beth A.1,2,3; Thompson, Paul D.1,2

Journal Club
Collapse Box


Statins are effective in reducing low-density lipoprotein cholesterol and cardiac events but can produce muscle side effects. We have hypothesized that statin-related muscle complaints are exacerbated by exercise and influenced by factors including mitochondrial dysfunction, membrane disruption, and/or calcium handling. The interaction between statins, exercise, and muscle symptoms may be more effectively diagnosed and treated as rigorous scientific studies accumulate.

©2012 The American College of Sports Medicine


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.

Connect With Us