Exercise and Sport Sciences Reviews

Skip Navigation LinksHome > July 2011 - Volume 39 - Issue 3 > Mitochondrial Protection by Resveratrol
Exercise & Sport Sciences Reviews:
doi: 10.1097/JES.0b013e3182141f80

Mitochondrial Protection by Resveratrol

Ungvari, Zoltan1; Sonntag, William E.1; de Cabo, Rafael2; Baur, Joseph A.3; Csiszar, Anna1

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Mitochondrial dysfunction and oxidative stress are thought to play important roles in mammalian aging. Resveratrol is a plant-derived polyphenol that exerts diverse antiaging activities, mimicking some of the molecular and functional effects of dietary restriction. This review focuses on the molecular mechanisms underlying the mitochondrial protective effects of resveratrol, which could be exploited for the prevention or amelioration of age-related diseases in the elderly.

©2011 The American College of Sports Medicine


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