Home > Subjects > Pharmacology > Some Pharmacokinetics of Sevoflurane in a Child with Severe...
A&A Case Reports:
doi: 10.1097/ACC.0b013e3182a706f6
Case Reports: Case Report

Some Pharmacokinetics of Sevoflurane in a Child with Severe Lipodystrophy

Steen, Evi R. MD; De Baerdemaeker, Luc E. C. MD, PhD, DEEA; Van Limmen, Jurgen MD; Wouters, Patrick MD, PhD

Collapse Box

Abstract

Lipodystrophies are acquired or inherited disorders characterized in part by the selective loss of adipose tissue and hypertriglyceridemia. The present case report of 2 sevoflurane anesthetics given to a child with such a disorder, before and after correction of severe hypertriglyceridemia, illustrates the considerable effects of increased serum lipids and decreased fat stores on the pharmacokinetics of sevoflurane.

© 2014 International Anesthesia Research Society

Login

Become a Society Member