A&A Case Reports

Skip Navigation LinksHome > March 15, 2014 - Volume 2 - Issue 6 > Some Pharmacokinetics of Sevoflurane in a Child with Severe...
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A&A Case Reports:
doi: 10.1097/ACC.0b013e3182a706f6
Case Reports: Case Report

Some Pharmacokinetics of Sevoflurane in a Child with Severe Lipodystrophy

Steen, Evi R. MD; De Baerdemaeker, Luc E. C. MD, PhD, DEEA; Van Limmen, Jurgen MD; Wouters, Patrick MD, PhD

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Abstract

Lipodystrophies are acquired or inherited disorders characterized in part by the selective loss of adipose tissue and hypertriglyceridemia. The present case report of 2 sevoflurane anesthetics given to a child with such a disorder, before and after correction of severe hypertriglyceridemia, illustrates the considerable effects of increased serum lipids and decreased fat stores on the pharmacokinetics of sevoflurane.

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