Antiphospholipid syndrome and heparin-induced thrombocytopenia are immune-mediated thrombotic conditions initiated by 2 distinct antibodies each targeting a discrete protein–antigen complex. Although produced by 2 different types of antibodies, they are similar in their autoimmune and pathophysiologic mechanisms. We present a case with simultaneous antiphospholipid syndrome and heparin-induced thrombocytopenia syndromes that sheds light on the correlation between these 2 syndromes.
From the *Department of Anesthesiology, University of Cincinnati, Cincinnati, Ohio; †Department of Anesthesiology, University of Nebraska, Omaha, Nebraska; and Departments of ‡Internal Medicine and §Emergency Medicine, University of Cincinnati, Cincinnati, Ohio.
Accepted for publication June 10, 2013.
Funding: There is no funding for this work.
The authors declare no conflicts of interest.
Address correspondence to Alaa A. Abd-Elsayed, MD, MPH, Department of Anesthesiology, University of Cincinnati, 231 Albert Sabin Way—Room 3212 MSB, Cincinnati, OH 45267-0531. Address e-mail to email@example.com.